Delta Plus Variant May Poses a Significant Threat: Scientists

The Possibility That the Delta Plus Have a Slight Advantage over Infected Individuals Who Were Previously Infected By COVID-19

India has been able to classify a newly diagnosed variant of the COVID-19 infection, which was initially identified by the World Health Organization in Europe, and termed it as a ‘variant of concern’, but it is still very early to be confirmed whether this new variant would pose to be a significant concern for the population. According to the health ministry of India, the research studies have been able to identify that this so-called Delta Plus variant of the coronavirus infection transmits at a much faster rate.

Rapid spreading of Delta Plus strain

The recently conducted studies have shown that the Delta Plus variant of COVID-19, which is also known as the AY.1, has the ability to transmit easily and rapidly and has a strong binding affinity with the lung parenchyma cells. After multiple testing, it has been confirmed that the Delta Plus variant is resistant to the monoclonal antibody therapy, which is a potent intravenous infusion of the antibodies that are used for neutralization of the viral strains.

This variant has been reported to be related to the Delta, which is an already existent variant of concern, which was initially identified in the population of India in the previous year during the second deadly wave of the coronavirus pandemic. The further transmission of the COVID-19 infection among the locals has been thought to be the cause of this rapidly transmitted Delta Plus variant.

The health ministry has stated that the Delta Plus variant of COVID-19, which was for the first time diagnosed in the South Asian country of India in the month of April, has also been found to be present in about 40 different samples which were taken from six districts across three stated, Madhya Pradesh, Kerala, and Maharashtra. Out of these, around 16 samples of the Delta Plus variant have been collected from the state of Maharashtra, which is one of the hardest-hit states of the country by the coronavirus pandemic.

The Delta Plus variant has also been detected in nine other nations across the world, including China, Russia, Nepal, Poland, Japan, Switzerland, Portugal, United Kingdom, and the United States. When compared with the original strain of the COVID-19 infection, it has been found that the Delta Plus variant is highly contagious and has now been reported to have been spread across 80 different countries throughout the world.

Viral mutations

All the viruses that are present in our environment are undergoing mutation at all times, and most of these mutated changes are bound to be inconsequential. In some cases, these mutated genetic changes even harm the virus itself. While other genetic mutations are able to make the infection or disease, they are spreading more infectious and even life-threatening in some conditions, and these mutated changes usually tend to be in domination.

A genetic mutation has the ability to elevate the virus from being a ‘variant of interest’ to a ‘variant of concern’, which is dining when it is able to show fulfilling evidence of complete one of the concerned criteria which has been previously set, and includes easily transmittable, increased severity of illness, reduction in being neutralized by antibodies and have a reduced amount of effectiveness in the treatment procedure or vaccination.

This has been questioned by leading virologists that the labeling of the coronavirus’s Delta Plus variant of concern, as there has been no proven data which could suggest that this Delta Plus variant tends to be more infectious or is able to lead more severity to the disease as compared with the other available COVID-19 variants.

Up till now, no new data has shown support for the claim made regarding the Delta Plus variant of concern, which has been confirmed by a virologist of the Royal Society of London. This means that more intensive data is required for the determination of the variant if it could be neutralized by the antibodies which are generated inside the human body after being administered with the available coronavirus vaccines or infection caused by another strain of the COVID-19 infection.

An extensive amount of data is required regarding the increase in the variant’s transmissibility and its diagnostic failures, which are not being picked up by routine tests, and whether the Delta Plus variant is causing a more severe form of the disease.

Read also Indian COVID Variant Of Global Concern: WHO Says